Punica granatum is the botanical name for pomegranate. It is mainly found in Iran, which is considered the main center of its origin. Ellagic acid, anthocycanins, punicalagins, and other chemicals found in pomegranate have a variety of therapeutic properties, including antioxidant, anti-inflammatory, and anti-angiogenesis. The incidence of acute renal failure (ARF) continues to rise every year. Some of the cases are associated with nephrotoxic effects caused by overdose, use of antibiotics. Antibiotic therapy that can be used to overcome this is pomegranate extracts. Renal failure is the inability of the kidneys to remove excess metabolites that accumulate in the blood. It is a systemic disease and the last common pathway of various diseases of the urinary tract and kidneys. It provokes violations of the electrolyte balance, acid-base and water balance, renal failure. One of the components of pomegranate is ellagic acid (EA), an ingredient that can protect cells from damage caused by free radicals. This ability will synergistically increase when combined with another powerful antioxidant pomegranate composition, the anthocyanidins. Pomegranate is rich in antioxidants that help fight and repair free radical damage from the sun and environmental factors such as hyperpigmentation and age spots. Studies have shown the effectiveness of punica granatum extract in protecting the skin from UVB-induced damage. Using cultured human skin fibroblasts, the researchers found that the polyphenols in the extract play an important role in creating a photoprotective barrier that protects the skin from sun damage and skin cancer. Anthocyanidins, ellagic acid and punicalagin in the extract simultaneously enhance microcirculation and renew cells. This stimulates the proliferation of keratinocytes in the epidermis and dermis to create new skin and give it an even tone. Collagen is a key protein that keeps skin firm and smooth without wrinkles or wrinkles. Ellagic acid not only inhibits collagen-degrading enzymes, but also prolongs the life of fibroblasts, maintaining the structural integrity and elasticity of the skin. Chronic inflammation caused by burns, sunlight, heat and other environmental pollutants can lead to premature aging. The body's defense mechanism reacts by releasing enzymes that trigger free radicals, causing further inflammation by releasing matrix metalloproteinases (MMPs). MMPs break down collagen and elastin fibers, which break down, thin and smooth the dermis. Anti-inflammatory compounds in pomegranates, such as polyphenolic antioxidants, inhibit pro-inflammatory cytokines and prevent dermis from thinning and loosening. Method of application: 1 capsule 2 times a day. Volume: 60 capsules. Tags: capsules, slimming
