Retinol A Gel is the new best friend of your skin. Retinol is a vitamin A derivative that cleans the pores, stimulates collagen to reduce wrinkles and speeds up cell renewal to smooth, brighten and smooth the skin - sometimes just for four weeks. How does retinal Provamed Rapid Clear Acne Retinol-A Gel function in the skin. When retinol is applied to the skin, it helps the skin to normalize the appearance, working in tandem with other ingredients that reduce numerous skin problems. Retinol also helps to maintain a fresh, healthier kind of skin and, naturally, eliminates problems such as dullness and rough texture. With retinol you will see an updated, youthful radiance, surprisingly smooth appearance and a perceptible sense of skin density. The importance of retinol (vitamin A) was discovered during the First World War, and subsequent studies showed that its deficiency causes xerosis and follicular hyperkeratosis. In 1968, a project of a retinoid drug was launched to synthesize compounds similar to vitamins A, by chemically manipulating its molecule to improve clinical efficacy and safety. The use of these substances in therapy dates back about 3000 years in ancient Egypt. However, the modern history of retinoids began in 1909, when a significant factor in the viability of the embryo in the fat extract of the egg yolk, called vitamin A. Vitamin A can not be synthesized by the body; so it should be applied to the skin. It is known that retinoids affect various cellular processes, such as cell growth and differentiation, cell surface changes and immune modulation. Many of their tissue effects are mediated by their interaction with specific receptors of cells and nucleic acids. Volume: 10 grams Tags: cream, hands, nails, dry skin, oily skin, normal skin